How
does Viagra work?
We know of the need to pump blood to the penis to make this hard, in order
to have sexual intercourse. Due to certain physical conditions this can
be impossible to achieve. However due to the development by Pfizer of their
product Viagra these conditions can be overcome.
Viagra was originally developed and trialled as a medication for hypertension
(high blood pressure). At some stage in these trials it was discovered that
men were experiencing erections. This discovery was to change the course
of the development of their product. It was found that Viagra worked by
causing the smooth muscle in the blood vessels to relax, increase the flow
of blood, also to lower blood pressure. Sildenafil, the active ingredient
in Viagra, is a PDE5 inhibitor; and it is this that specifies an increase
in blood flow to the penis. When a man is sexually aroused his penile arteries
relax and enlarge. At the same time Viagra causes the veins that remove
blood from the penis compress, acting as a valve, thus they are restricting
the flow of blood from the penis causing an erection. Previously it had
been thought that erectile dysfunction was purely psychological but the
development of Viagra refutes this. We now know that the nerves and blood
vessels play a key role. If the nerves and blood vessels do not operate
correctly dysfunction occurs, this malady can now be rectified by the correct
use of Viagra.